منابع مشابه
Transgenic silkworms producing sericin cocoons applicable for tissue engineering
Specific gene functions have been successfully suppressed by gene silencing or editing in many organisms. However, genetic manipulation to suppress the function of a target tissue has not been achieved using genes such as cytotoxin family members. We established transgenic silkworms with posterior silk glands (PSGs) that express the enzymatic domain of the cytotoxin pierisin-1A (P1A), a recentl...
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The aim of this study was to synthetize porous three-dimensional composites, similar with natural bone structure, for using it in tissue engineering. The new composites prepared by freeze-drying of composite gels consist of a mineral phase nanohydroxyapatite and an organic phase type I fibrillar collagen and silk sericin, the latter acting as a glue-like protein that serves as an adhesive, for ...
متن کاملfabricating electrospun poly(3-hydroxybutyrate)/hydroxyapatite nanocomposite scaffold for tissue engineering application
. در رســاله ی حاضر، ابتدا داربست نانوالیاف سه بعدی متخلخل به روش الگوبرداری تصویری شبیه سازی شد. با استفاده از طراحی آزمایش به روش تاگوچی پس از ساخت داربست های پلی (3- هیدروکسی بوتیرات) (p3hb) شناسایی رفتار پارامترهای موادی مثل لزجت سیال پلیمر، فراریت و رسانایی الکتریکی محلول پلیمری و پارامترهای دستگاهی مثل دبی حجمی سیال، ولتاژ الکتریکی و فاصله نازل تا جمع کننده صورت گرفت. بعد از محاسبه ی خصوص...
Modification of sericin-free silk fibers for ligament tissue engineering application.
Biomedical application of silk requires the removal of sericin that is the gumming material of native silk fibers. This is because sericin can elicit an adverse immune response after implantation in the human body. However, the removal of sericin causes the silk fiber to fray and weakens its structural property, making it very difficult to knit or braid them into a scaffold for ligament tissue ...
متن کاملAdult Mesenchymal Stem Cells for Tissue Engineering
The identification of multipotential mesenchymal stem cells (MSCs) derived from adult human tissues such as bone marrow and connective tissues has provided exciting prospects for cell-based tissue engineering and regeneration. This review article focuses on the biology of MSCs, their differentiation potentials in vitro and in vivo, and their application in tissue engineering...
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ژورنال
عنوان ژورنال: Applied Sciences
سال: 2020
ISSN: 2076-3417
DOI: 10.3390/app10238457